Clinical Trials

Clinical trials test new treatments before they are widely available. Our center takes part in trials of new medicines, survey studies that follow people on their usual treatment, and our own research studies. Joining is always your choice, and you can leave a study at any time. Whether a study fits you depends on your diagnosis, past treatments and overall health.

Interested in a study?
Call 781.744.8444 or ask at your next visit. Our research team will check whether a study may be right for you.

Trials of new medicines

EnrollingLichen planopilaris

Oral brepocitinib

Tests whether a pill called brepocitinib can calm the inflammation behind lichen planopilaris. Some people get the study pill and some get a placebo, a look-alike pill with no medicine. For adults 18 and older whose diagnosis was confirmed by a scalp biopsy.Phase 2/3 · Priovant Therapeutics · Study details on ClinicalTrials.gov (NCT07532603)

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Fully enrolledAlopecia areata

Bempikibart (ADX-914)

Tested an antibody medicine, given as a shot under the skin, in adults with severe alopecia areata. It targets part of the immune response that attacks hair follicles. This study is no longer taking new patients.Phase 2a · Q32 Bio · Study details on ClinicalTrials.gov (NCT06018428)

Survey studies

EnrollingAlopecia areata, adults

CorEvitas AA Registry

A survey study for adults starting a new alopecia areata medicine. There is no study drug. You stay on the treatment you and your doctor chose, and answer questions about your hair and health at regular visits. This shows how well these medicines work and how safe they are over time.Survey study · CorEvitas · Study details on ClinicalTrials.gov (NCT05745389)

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EnrollingAlopecia areata, adolescents

CorEvitas Adolescent AA Registry

A survey study for teens ages 12 to 17 with alopecia areata. There is no study drug. Teens stay on the treatment they and their doctor chose, and families answer questions at regular visits.Survey study · CorEvitas · Study details on ClinicalTrials.gov (NCT06562270)

Our own studies

Investigator ledAlopecia areata

How JAK inhibitors work

We follow people starting a JAK inhibitor pill and study how the medicine changes inflammation in the scalp.Lahey Hair Loss Center of Excellence
Investigator ledFemale pattern hair loss

Hair loss and the renin angiotensin system

We study whether the renin angiotensin system, a hormone system that helps control blood pressure, plays a role in thinning hair in women.Lahey Hair Loss Center of Excellence
Investigator ledMenopause

Hormone therapy and hair counts

We measure how hair density changes over time in women who use hormone therapy for menopause.Lahey Hair Loss Center of Excellence

Recently completed

PublishedFrontal fibrosing alopecia

Delgocitinib cream

Tested a JAK inhibitor cream applied to the scalp in women with frontal fibrosing alopecia. The cream lowered a key inflammation marker. Published in the Journal of Investigative Dermatology, 2026.LEO Pharma · PMID 41101628

What these terms mean

  • Randomized: a computer assigns each person to a study group by chance.
  • Placebo controlled: some participants receive an inactive treatment so results can be compared fairly.
  • Phase: early phase studies focus on safety and dosing; later phases test how well a treatment works in more people.
  • Survey study: researchers collect information about your usual care and ask you questions. You do not get a study drug.
  • Antibody medicine: a lab-made protein, given as a shot, that blocks one specific part of the immune system.

"Enrolling" means the study is open on ClinicalTrials.gov; openings at our site can change. Study details are from ClinicalTrials.gov as of October 2026. Enrollment changes often, so please contact us for the current status.