Walker CJ, Flanagan KE, Pathoulas JT, Wiss IP, Senna MM. Hair Growth in a Patient with Alopecia Areata on Tocilizumab. Skin Appendage Disord. 2021;7(5):408-412.
Abstract
INTRODUCTION: Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ.
CASE PRESENTATION: Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis.
DISCUSSION: Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.
